Sulforaphane and its glutathione conjugate but not sulforaphane nitrile induce UDP-glucuronosyl …
The intermediate then breaks down to the isothiocyanate sulforaphane, or to the nitrile, depending on several factors such as pH and specific proteins (Scheme 1). The biological activity of the nitrile has received little attention, but is a poor inducer of quinone reductase in Hepa1c1c7 cells .